Protein and Ligand Preparation for Glide

The quality of Glide results depends on reasonable starting structures for both the protein and the ligand. Schrödinger offers a comprehensive protein preparation facility in the Protein Preparation Workflow Panel, which is designed to ensure chemical correctness and to optimize protein structures for use with Glide and other products. Likewise, Schrödinger offers a comprehensive ligand preparation facility in the LigPrep Panel. It is strongly recommended that you process protein and ligand structures with these facilities in order to achieve the best results.

This section contains the following topics: