Uninstalling Schrödinger Software on Windows

Before uninstalling Schrödinger software, ensure that all Schrödinger applications and supporting programs are not running: this includes utilities, Maestro, Schrodinger Command Prompt or SchrodingerShell windows, and any other Schrödinger applications. If remote jobs are running, you should wait until they finish before uninstalling Maestro, otherwise the results will not be copied back to the working directory or incorporated into the project.

If you want to kill all Schrödinger applications and supporting programs, navigate to the mmshare-vversion\bin\WIN32-x86 folder in your Schrödinger software installation and run SchrodingerProcKill.

If you have installed the third-party databases required by Prime (or any other software or data) into the Schrödinger installation, the uninstaller does not remove them, and you must remove them manually from the installation. You should do this before running the uninstaller, otherwise the installation is not entirely removed.

/You cannot use Add/Remove Programs to uninstall the software: this has been explicitly disabled, because setup.exe performs some tasks that are not performed with Add/Remove Programs. You must therefore use setup.exe or its equivalent, as explained below.

To uninstall, you can use one of the following methods:

  • Run the uninstaller by going to Start → All Programs → Schrodinger-release→ Uninstall.

  • Run the uninstall.exe program, which is located in the installer folder of your Schrödinger software installation (%SCHRODINGER%\installer).

  • Run the setup.exe program that you used to install the software.

  • Run uninstall-silent.exe from a DOS window (not a Schrodinger Command Prompt window). This program is also in the installer folder of your Schrödinger software installation. It accepts the same arguments as setup-silent.exe, given in Table 1, except that the default and only allowed action is /remove, so you do not need to specify the action.

When you uninstall Schrödinger software you can choose whether to uninstall Maestro and the various applications. Selecting Maestro does not uninstall other applications, which must be selected separately. To uninstall the entire software package, you should ensure that you uninstall the other applications as well as Maestro.