General Preferences

This tab is used to set general preferences.

History settings

This section provides settings for storage of recently used items for later use.

Command history

These options can be used to limit the number of commands stored, and therefore available in the Command Script Editor panel.

  • Unlimited—Store all commands.
  • Limited—Store the number of commands given in the text box. When this limit is exceeded, the oldest commands are removed from the history.
Recently used list

In this text box, you can specify how many items are displayed on the lists of recently used projects and recently imported files, which are displayed with and .

Directories settings

These settings determine some of the directories that are used by Maestro. Maestro checks folder permissions when you change these settings. If a folder cannot be updated, a warning appears:

Read-only: A warning appears, but the folder updates.

Does not exist / No access: A warning appears, the update is blocked, and Maestro switches back to your last valid setting.

Temporary (scratch) project location text box and Browse button

Specify the location for the storage of temporary (scratch) projects. Click Browse to navigate to the desired location. This directory should be large enough for your temporary projects, and for efficiency should be on a local file system. This location is used for temporary projects the next time Maestro starts.

If the SCHRODINGER_TEMP_PROJECT environment variable is set, this control is disabled and the location defined by the variable is displayed. Otherwise, the default location on Linux and Mac is $HOME/.schrodinger/tmp, and on Windows is %LOCALAPPDATA%\Schrodinger\tmp.

Custom folder options

Specify the location of the custom directory used in file selectors. The contents of this directory are displayed when you click the Custom icon in a file selector under Look in.

  • Maestro installation directory—Set the custom directory to the Maestro installation directory.

  • Maestro launch directory—Set the custom directory to the directory from which Maestro was started, on Linux, or the Schrodinger folder in your Documents folder on Windows and Mac.

  • Other—Specify the directory in the text box or click Browse to select a directory.

File chooser dialogs (Windows only) options

Set options for the use of native Windows file choosers when there are options associated with reading or writing files. The use of a custom file chooser can be slow at times.

  • Avoid custom file dialogs—When possible, use the native Windows file dialog box, and present the options for the action in a separate dialog box. This option is selected by default. If this option is not selected, the custom file chooser with the options included is used.

  • Skip confirmations - always use defaults—Once the files have been chosen in the Windows native file chooser, read or write the files immediately with the last settings used. If this option is not selected, a second dialog box opens after the selector, to make settings for the file operations.

File extensions settings

These settings control Maestro's default file suffix for several different file formats. A default suffix is automatically appended to a file name if that file name has no suffix. The default file suffixes are:

  • Maestro — mae
  • Maestro compressed — maegz
  • PDB — pdb
  • Mol2 — mol2
  • SD — sdf
  • SD compressed — sdfgz
Appearance settings

These settings control the appearance or layout of Maestro.

Show tooltips option

When the pointer is paused over a control, show information about the control in a box near the control after a short delay. The box is hidden after a period of time, or when the pointer is moved. This information in a box is known as a tooltip or balloon help.

Main title bar information options

Show the selected information in the title bar of the main window, in addition to the application name and suite (Maestro, Maestro BioLuminate, etc.) and the project name. The options are:

  • Maestro version number
  • Current working directory
  • Full project path

The order in which the information is shown is version number, project path, directory. The full project path replaces the project name.

Application fonts settings

Set the font, size, and style for the text. The Regular settings control the fonts in all the application panels: headings, button labels, menu items, and so on. The Text editing settings control the fonts in all places where you can edit text (text boxes, tables, and so on). The Project Table settings control the fonts for the text that is displayed in the column headings and the table cells in the Project Table. The Toolbar buttons settings control the fonts for the text that is displayed on toolbar buttons.

An example of the font size is given under each option menu. You must restart Maestro to apply the new fonts.

Panels settings

Control the docking, location, and choice of panels.

Allow docking of panels option

This option allows panels to be docked into the Workspace. Most of the panels other than those on the Applications or Tasks menu are dockable. This option is selected by default. If it is not selected, when you open these panels, they are opened outside the Workspace and cannot be attached to the Workspace (docked).

Location options

Specify the location to place the docked panels. They can be docked in either the main window, or in a floating window, named Docked Panels.

Show dialog boxes at the position of the pointer

When a dialog box opens, center it on the current pointer position. If you turn this option off, the dialog box is displayed at its last displayed location (or its default location if it has not been displayed).

Always show panels on top of main window

Show all panels in front of the main window, and ensure that they do not go behind the main window.

Quitting Maestro settings

Select the information that is shown or saved when Maestro quits.

Warn when quitting Maestro option

Display the Quit panel when quitting Maestro, which provides an opportunity to cancel the quit operation.

Save panel layout option

Save the panel layout (size, location) of all panels that have been opened in a Maestro session in a resource file when Maestro quits. The layout is read the next time Maestro is started. You can also save the layout by choosing Window → Save Layout.

Write command log file option and text box

Write a log of commands used in the Maestro session to the log file specified in the text box. The log file is written to Maestro's working directory. This information can be useful to Schrödinger support staff when responding to any problem you report.

Maestro Assistant settings

Settings for the Maestro Assistant AI-powered chat interface.

Enable Maestro Assistant (Beta) option

Select this option to enable the Maestro Assistant. When enabled, the assistant is available from the Help menu, the panel help button menus, and the Workspace toolbar. When disabled, the assistant is hidden from all locations. Only natural language text queries are processed by the external LLM. Proprietary 3D structures, coordinates, project files, and sequence data remain completely local and are never used to train public models.