Shape Screening
Shape Screening is a ligand-based workflow for efficiently screening ultra-large purchasable or synthesizable compound libraries. Chemically-intuitive ligand alignments are scored based on the quality of the shape overlap against a reference ligand. Shape Screening identifies potential hit molecules with activity even when they are topologically dissimilar to the known reference ligand, making it a powerful ligand-based screening method.
Shape Screening requires a Shape Screening license and has no additional product dependencies.