cphmd_calc_pka.py Command Help
Command: $SCHRODINGER/run -FROM scisol cphmd_calc_pka.py
usage: cphmd_calc_pka.py [-h] -p PREFIX -outprefix OUTPREFIX [-pka0 PKA0]
[-n0 N0] [-xcolid XCOLID] [-ycolid YCOLID] [-protS]
Program for calculating pKa by fitting titration curves. Run in the directory
where the constant pH MD simulation was run. This directory must contain
<prefix>_site*.txt files, one per pH.
options:
-h, --help show this help message and exit
-p PREFIX, -prefix PREFIX
Prefix for input lambda statistics files
-outprefix OUTPREFIX Prefix for output pKa files
-pka0 PKA0 Initial pKa value (default: pH where the S value is
the closest to 0.5)
-n0 N0 Initial hill coeficient (default: 1.0)
-xcolid XCOLID Colid for pH (default: 1)
-ycolid YCOLID Colid for deprotonation fraction (default: 3)
-protS Input S fraction is for the protonated state