cysteine_mutation_backend.py Command Help
Command: $SCHRODINGER/run cysteine_mutation_backend.py
usage: cysteine_mutation_backend.py [-h] [-flex_dist FLEX_DIST]
[-flex_adj_res FLEX_ADJ_RES]
[-cys_to_x CYS_TO_X]
[-refine_mut {python_minimize,prime_minimize,none}]
[-res_pairs RES_PAIRS] [-j] [-NOJOBID]
[-HOST <host_list>] [-LOCAL] [-OVERWRITE]
[-RESTART] [-no_cleanup]
[infile]
This script is used by cysteine_mutation_gui.py.
positional arguments:
infile Input structure file
options:
-h, --help show this help message and exit
-flex_dist FLEX_DIST Optimize atoms within this distance of the mutated
residues (by default, only mutated residues are
optimized)
-flex_adj_res FLEX_ADJ_RES
Optimize residues that are within this distance, by
sequence (by default, only mutated residues are
optimized)
-cys_to_x CYS_TO_X Mutate each cysteine to each of these residue types
(comma-separated)
-refine_mut {python_minimize,prime_minimize,none}
Refinement method. Available options:"python_minimize"
(default) - Minimize using the Python Minimizer
(ffld); "prime_minimize" - Refine with Prime
minimization; "none" - Do not minimize nor calculate
energies (for debugging).
-res_pairs RES_PAIRS Residues to mutate (comma-separated)
-j , -jobname The job name.
-NOJOBID Run the script without job control
-HOST <host_list> Run job remotely on the indicated host entry.
-LOCAL Do not use a temporary directory for job files. Keep
files in the current directory.
-OVERWRITE Overwrite any existing job files.
-RESTART Attempt to restart the previous job. All arguments
other than the jobname are ignored when -RESTART is
specified. NOTE: For job to be restartable, it must
have been started with -LOCAL.
-no_cleanup Do not clean up intermediate Prime subjob files.