oned_screen create Command Help
Command: $SCHRODINGER/oned_screen create
usage: oned_screen create [-h] -source <input> -dest <output>.1dbin
[Creation Options]
[Job Control Options]
Optional Arguments:
-h, --help Show this message and exit.
Required Arguments:
-source <input> File of structures from which to create the 1D data
file. Supported formats are SMILES, SMILES-CSV,
Maestro and SD. When building an ultra-large 1D
library, the recommended approach is to create a
series of smaller 1D data files containing 10-50
million rows apiece, rather than a single file
containing potentially billions of rows. This ensures
the fastest multi-CPU screens. For Maestro and SD
formats, the number of input structures must not
exceed 2,147,483,647.
-dest <output>.1dbin Name of the 1D data file to create. Must include an
absolute path if -nocopy is supplied.
Creation Options:
[-treatment {pharm,element,mmod}] [-fd <fd_file>] -props <list> [-nocat]
-treatment {pharm,element,mmod}
Treat each structure as a set of Phase pharmacophore
features, as a set of atoms distinguished by elemental
type, or as a set of atoms distinguished by Macromodel
type (default: pharm).
-fd <fd_file> Use pharmacophore feature definitions in the supplied
file, rather than the default definitions in the
software distribution. Applicable only when the
treatment is pharm.
-props <list> Comma-separated list of properties in the source file
that should be stored in the 1D data file. Property
names must be of the form <t>_<source>_<name>, where
<t> is the property type ("b", "i", "r", "s"),
<source> indicates the origin of the property
("phase", "user", etc.), and <name> is a descriptive
name ("Fitness", "pIC50", etc.). By default, the 1D
data file will contain the SMILES, name and a 1D
encoding of each structure.
-nocat If distributing creation over multiple subjobs,
combine subjob 1D data files using conventional line-
by-line I/O rather than direct concatenation of each
file's entire contents. Use of this option ensures
that the final 1D data file is compatible with
previous releases, but it is much slower.
Job Control Options:
[-HOST <host>[:<n>]] [-TMPDIR <tmpdir>] [-JOBNAME <jobname>] [-nocopy]
[-NJOBS <njobs>]
-HOST <host>[:<n>] Run job remotely on the indicated host entry. Include
:<n> to distribute the job over <n> CPUs.
-TMPDIR <tmpdir> Store temporary job files in <tmpdir>.
-JOBNAME <jobname> Override default job name.
-nocopy Do not copy source or destination 1D data files
between the local host and job host. 1D data file
names must include an absolute path that exists on the
job host and on all compute nodes of that host.
-NJOBS <njobs> Divide the overall job into <njobs> subjobs.