piper.py Command Help
Command: $SCHRODINGER/run -FROM psp piper.py
usage:
$SCHRODINGER/run -FROM psp piper.py -receptor <receptor pdb> -receptor_chains <chain ids for receptor> -ligand <ligand pdb> -ligand_chains <chain ids for ligands> [<other options>]
Use -h option for full description of options.
options:
-h, --help show this help message and exit
-receptor RECEPTOR The receptor protein used in docking (.pdb file). If
running in antibody mode this is the antibody.
-receptor_chains RECEPTOR_CHAINS
Comma-separated list of chains to use in the receptor.
Do not use spaces, use an underscore (_) for a blank
chain name.
-ligand LIGAND The ligand protein used in docking (.pdb file). If
running in antibody mode this is the antigen. Not used
for Multimer/symmetry calculations.
-ligand_chains LIGAND_CHAINS
Comma-separated list of chains to use in the ligand.
Do not use spaces, use an underscore (_) for a blank
chain name. Not used for Multimer/symmetry
calculations.
-use_nonstandard_residue USE_NONSTANDARD_RESIDUE
Whether or not to use nonstandard residues in the
docking calculation. The default is no.
-s {C2,C3} Run docking in C2 (dimer) or C3 (trimer) mode.
-antibody Run in antibody mode.
-nomask_cdr In antibody mode, do not mask the CDR region
-rotations ROTATIONS Number of rotation matrices to use from rotation file.
Default is 70000
-poses POSES Number of poses to return. Default is 30.
-constraints_file CONSTRAINTS_FILE
The file name that contains the definitions for each
attraction/repulsion defined. This is a JSON formatted
file and should be an array of objects. Each object is
required to have the keywords "asl", "constraint_type"
and "protein_type", and can optionally have the
keyword "attraction".
-constraints_file_example
Print an example constraints file.
-atom_prm ATOM_PRM Path to atom parameters file
-rot_prm ROT_PRM Path to rotations parameter file
-coeffs_prm COEFFS_PRM
Path to coefficients parameter file
-protein_interaction_analysis PROTEIN_INTERACTION_ANALYSIS
Whether to include protein interaction analysis in
output yes or no (default)
-score_in_place SCORE_IN_PLACE
Whether to score the input structure in addition to
docked poses. yes or no (default)
-refinement_protocol {minimize,vacuum_minimize,interface,none}
Refinement protocol to run after the docking is
complete. Options: none, interface (default),
vacuum_minimize, or minimize
-raw Store ALL piper poses for each cluster in pose-viewer
format. This setting will override the refinement
option and set it to none.
-no_wam If set, WAM property will not be written to output
structure
-v show program's version number and exit
-jobname JOBNAME, -JOBNAME JOBNAME, -j JOBNAME
Set the base name of outputs
-OMPI OMPI, -ompi OMPI
Run job using using this number of processors
Job Control Options:
-HOST <hostname> Run job remotely on the indicated host entry.
-WAIT Do not return a prompt until the job completes.
-D, -DEBUG Show details of Job Control operation.
-NOJOBID Run the job directly, without Job Control layer.
Standard Options:
-NOLAUNCH Set up subjob inputs, but don't run the jobs.